Homology Modeling of Coagulase in Staphylococcus aureus
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چکیده
منابع مشابه
Homology Modeling of Coagulase in Staphylococcus aureus
The close correlation between the ability of coagulase to clot blood plasma and their capacity to produce disease, and the corresponding absence of this property in nonpathogenic strains, have led to the assumption that the coagulase, plays important role in the pathogenesis of disease. Currently, crystal structure of coagulase in Staphylococcus aureus remains indefinable. Thus, the objectives ...
متن کاملVariation of bound coagulase of Staphylococcus aureus.
Duthie (1954) reported that bound coagulase (clumping factor) of staphylococei is released from the surface of autolysing cells into the medium of old broth cultures. Rosenblum and Jackson (1957) noticed occasional alteration of bound coagulase and pigment production after storage of staphylococci for months to years. Decrease in bound coagulase activity of freshly isolated hospital strains of ...
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22 A novel rapid PNA FISH method, Staphylococcus QuickFISH, for the direct 23 detection of Staphylococcus species from positive blood culture bottles was 24 evaluated in a multicenter clinical study. The method utilizes a microscope slide 25 with pre-deposited positive and negative control organisms and a self-reporting 26 15 minute hybridization step which eliminates the need for a wash step. ...
متن کاملDabigatran inhibits Staphylococcus aureus coagulase activity.
The ability of Staphylococcus aureus to clot plasma through conformational activation of prothrombin by staphylocoagulase is used to distinguish S. aureus from coagulase-negative staphylococci. We show that while the direct thrombin inhibitor dabigatran inhibits staphylocoagulase activity, the clinical use of dabigatran etexilate is not expected to interfere with direct tube coagulase testing.
متن کاملComparison of selective media for coagulase-positive enterotoxigenic Staphylococcus aureus.
Different culture media were used to detect enterotoxigenic Staphylococcus aureus strains from peptone salt solution and inoculated minced meat. When recovery, reactions, and counting mistakes were considered, it was concluded that Baird-Parker agar was the best medium.
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ژورنال
عنوان ژورنال: Bioinformation
سال: 2012
ISSN: 0973-8894,0973-2063
DOI: 10.6026/97320630008412